ISBN: Ostalo
Godina izdanja: 2019
Jezik: Engleski
Autor: Strani

"Lifespan: Why We Age—and Why We Don`t Have To by Harvard genetics professor Dr. David A. Sinclair (published by Thorsons) argues that aging is a treatable disease rather than an inevitability. Sinclair posits that cellular decay is driven by a loss of epigenetic information and explores how to activate ancient `longevity genes` to slow or reverse the aging process.Key Concepts from the BookThe Information Theory of Aging: Sinclair compares DNA to the digital data on a CD and the epigenome to the player that reads it. Over time, cellular damage and epigenetic noise cause the `scratches` that lead to aging.Vitality Genes: The book focuses on sirtuins and other longevity genes that are normally turned on during times of stress but become less effective over time.Practical `Hormesis` InterventionsSinclair highlights several lifestyle changes designed to trigger these survival circuits without causing cellular damage—a process known as hormesis:Intermittent Fasting & Caloric Restriction: Limiting eating windows to activate survival pathways.Temperature Exposure: Regular exposure to cold and heat (e.g., saunas or cold plunges).Exercise: Sustained physical activity designed to elevate heart rate and stimulate cellular repair.Reviews and Community PerspectiveCriticism: Many in the scientific and medical community argue that Sinclair`s claims regarding `age reversal` in mice and his theories about genes conserved across species are premature and lack sufficient human data.Popularity: Despite scientific controversy, the book is considered highly influential in the anti-aging and longevity community, inspiring many people to track biomarkers and adjust daily habits."